Nanobiophysics and Nanobiotechnology Labortory

The structural Biophysics and Nanoscience laboratory strives to understand the structural and functional aspect of biologically active molecules when they interact with metallic nanoparticle under physiological environment. Currently, the main structural techniques like fluorescence spectroscopy, FTIR Imaging, AFM, DLS, DSC, XRD, Gel electrophoresis (both 2-D and one dimension) and UV Visible spectroscopy are used to understand the structural and functional aspects of biomolecules viz.: protein, nucleic acids and amino acids. Our chief goals are to investigate how nanomaterials interact with various biological systems like cell and cell membranes, proteins, nucleic acids and to investigate biophysical mechanisms of interactions. Further our goal is to develop applications of nanoparticles in biology and medicine.

Research Project (Ongoing)
1) Study of biomacromolecules bound to metallic nanoparticles.
2) A biophysical approaches to assays of venom toxicity.
     Collaborators: Haffkines Institute, parel, Mumbai
3) Proteomic study in eukaryotic model.
Research Project (Completed)
1) A study of interaction of nanoparticles with serum albumin and amino acids.
2) Impact of UV radiation on structural and functional properties of biologically active molecules in presence of nanoparticles.